Clearance of stored red blood cells is not increased compared with fresh red blood cells in a human endotoxemia model
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چکیده
منابع مشابه
Arachnoid clearance of red blood cells.
Labelled red blood cells were instilled intraventricularly in groups of dogs and monkeys for evaluation of transfer to the vascular compartment. Blood levels were minimal (5% of the original material) with low-pressure infusions. A large movement (above 25%) of the type originally described by Simmonds occurred with high-pressure intraventricular infusions, cisternal injections, or after the in...
متن کاملHuman red blood cells-1
Biochemists and cell biologists, who are interested in membranes, tend to regard the human red blood cell ambivalently. On one hand, red blood cells lack nuclei and the various intracellular organelles, yet that are highly specialized for a particular respiratory function. On the other hand, the human red blood cell presents an excellent model for membrane transport function.
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Introduction: The aim of the current study was to investigate the effects of X-ray radiation on some hematological parameters, morphology of red blood cells (RBC) and erythrocyte sedimentation rate (ESR) analysis of human blood using computed tomography (CT) scanner. Material and Methods: For the purpose of the study, 5 ml of wholeblood was drawn from vein puncture of 28 healthy people and div...
متن کاملAlterations in cell surface area and deformability of individual human red blood cells in stored blood
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusion. To systematically investigate changes in stored whole blood, the hematological properties of individual RBCs were quantified in blood samples stored for various periods with and without a preservation solution called CPDA-1. With 3-D quantitative phase imaging techniques, the op...
متن کاملAccelerated clearance of human red blood cells in a rat transfusion model
BACKGROUND Animal models are valuable in transfusion research. Use of human red blood cells (RBCs) in animal models facilitates extrapolation of the impact of storage conditions to the human condition but may be hampered by the use of cross species. METHODS Investigation of clearance and posttransfusion recovery in a rat model using fresh and stored human RBCs. RESULTS Directly following tr...
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ژورنال
عنوان ژورنال: Transfusion
سال: 2016
ISSN: 0041-1132
DOI: 10.1111/trf.13595